产品货号：
Z34446
中文名称：
TBP-1/PSMC3抗体
英文名称：
Anti-TBP-1/PSMC3 Antibody (Clone#4D3)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TBP-1/PSMC3 Antibody (Clone#4D3) |
| 指标别名 | Proteasome subunit P50;PSMC3;Tat binding protein 1;TBP 1;TBP1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | PSMC3 |
| 克隆号 | 4D3 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human TBP-1/PSMC3 recombinant protein (Position:M1-A439). |
| 实际分子量 | 50KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | 26S protease regulatory subunit 6A,also known as 26S proteasome AAA-ATPase subunit Rpt5,is an enzyme that in humans is encoded by the PSMC3 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes,a 20S core and a 19S regulator.The 20S core is composed of 4 rings of 28 non-identical subunits;2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.The 19S regulator is composed of a base,which contains 6 ATPase subunits and 2 non-ATPase subunits,and a lid,which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome,the immunoproteasome,is the processing of class I MHC peptides.This gene encodes one of the ATPase subunits,a member of the triple-A family of ATPases that have chaperone-like activity.This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex.A pseudogene has been identified on chromosome 9. |
| Uniprot ID | P17980 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | proteasome 26S subunit,ATPase 3 |
| 蛋白名全称 | 26S proteasome regulatory subunit 6A |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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